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 | Dr. Jitendra K. Thakur
Staff Scientist III, Plant Mediator Lab
M.Phil., Ph.D. University of Delhi South Campus
Phone: 91-11-26741612/14/17 Extn. 221
Direct: 91-11-26735221
Email: jthakur@nipgr.res.in |
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 Career |
 | Scientist (Oct 2009 - present): National Institute for Plant Genome Research, New Delhi, India. |
| Assistant Professor (Sep 2008- Sep 2009): Indian Institute of Science Education & Research - Kolkata, Mohanpur, India. |
| Research Fellow (Jan 2004 - Aug 2008): Harvard Medical School/MGH Cancer Center, Boston, USA. |
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| Awards, Scholarships & Fellowships |
| International |
| Fellowship for Medical Discovery (ECOR-FMD), Massachussets Genreal Hospital, Boston, USA. 2006-2008 |
| Financial Aid Award, Cold Spring Harbor Laboratory, New York, USA. 2006 |
| Keystone Scholarship 2002 |
| IAPTC&B Fellowship 2002 |
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| National |
| Innovative Young Biotechnologist Award (IYBA) from DBT, Govt. of India. 2008 |
| INSA (Indian National Science Academy) medal for Young Scientist. 2008 |
| Junior and Senior Research Fellowships, CSIR-UGC-NET, 2000-2003 |
| DBT scholarship for M.Sc.(Biotechnology). 1994-1996 |
| Membership of Academic Honours Society of Mathematics on the basis of merit. Christian College, Lucknow. 1993 |
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| Research Interests |
| Our lab is interested in understanding the molecular mechanism of gene regulation in plants, specifically focusing on the important roles played by the co-factors in the transcriptional activity of the transcription factors. The lab is paying special attention to the plant Mediator complex, a large multi-protein complex which works as a bridge between the transcriptional regulators and RNA polymerase II. Our long term objective is to understand the structural-functional relationship of transcription factors and Mediator interface. |
| Scientific Publications |
| Naar AM and Thakur JK (2009) Nuclear Receptor-Like transcription factors in fungi. Genes & Development 23: 419-32. |
| Thakur JK, Arthanari H, Yang F, Chau KH, Wagner G and Näär AM (2009) Mediator subunit Gal11p/MED15 is required for fatty acid-dependent gene activation by yeast transcription factor Oaf1p. J Biol Chem 284: 4422-4428. |
| Thakur JK, Arthanari H, Yang F, Breger J, Fan X, Sun J, Li D, Struhl K, Moye-Rowley S, Mylonakis E, Cormack B, Wagner G and Naar AM (2008) A nuclear receptor-like pathway regulating multidrug resistance in fungi. Article in Nature 452: 604-609. [Covered in News & Views section by Andre Goffeau, Nature, 2008, 452: 541-542; in Perspective section by Monk and Goffeau, Science, 2008, 321: 367-369] [F1000 factor 9.8 Exceptional;] |
| Thakur JK, Jain M, Tyagi AK and Khurana JP (2005) Exogenous auxin enhances the degradation of a light down-regulated and nuclear-localized OsiIAA1, an Aux/IAA protein from rice, via proteasome. Biochemica et Biophysica Acta 1730: 196-205. |
| Thakur JK, Malik MR, Bhatt V, Reddy MK, Sopory SK, Tyagi AK and Khurana JP (2003) A POLYCOMB group gene of rice, OsiEZ1, codes for a nuclear-localized protein expressed preferentially in young seedlings and during reproductive development. Gene 314: 1-13. |
| Thakur JK, Tyagi AK and Khurana JP (2001) OsIAA1, an Aux/IAA cDNA from Rice, and Its Expression as Influenced by Auxin and Light. DNA Research 8(5): 193-203. |
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| Book Chapters |
| Khurana JP, Tripathi L, Kumar D, Thakur JK and Meghna R. Malik. Cell Differentiation in Shoot Meristems - A Molecular Perspective.In Plant Biotechnology and Molecular Markers, In: Srivastava, P.S., Narula, A. and Srivastava, S. (eds.), Plant Biotechnology and Molecular Markers, pp. 366-385, Anamaya Publishers, New Delhi. |
| Tyagi AK, Khuarana JP, Sharma AK, Mohanty A, Dhingra A, Raghuvanshi S, Mukhopadhyay A, Gupta V, Anand S, Kathuria H, Bhushan S, Thakur JK and Kumar D. Organ-specific gene expression and genetic transformation for improvement of rice. In: Khush, G.S., Brar, D.S. and Hardy, B. (eds), Advances in Rice Genetics, pp. 552-555, International Rice Research Institute, Manila. |
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| Research in news media |
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